What is Lewy Body Dementia? Symptoms, Causes, Diagnosis, and Care

Written by Nguyenjessica 

Published on July 18 2025

When people think of dementia, Alzheimer’s disease is usually the first condition that comes to mind. However, Lewy Body Dementia (LBD) is actually the second most common type of progressive dementia, accounting for up to 20% of all dementia cases. Despite its prevalence, LBD often remains underdiagnosed or misdiagnosed due to its complex and overlapping symptoms with both Alzheimer’s and Parkinson’s disease.

Lewy Body Dementia doesn’t just affect memory. It impacts cognition, movement, behavior, and even sleep. For patients and families, understanding the symptoms of LBD is crucial to seeking timely diagnosis and appropriate care. In this article, we’ll take an in-depth look at the symptoms of Lewy Body Dementia, what causes it, how it’s diagnosed, and how to manage it effectively.

Key Points

Lewy Body Dementia is the second most common type of dementia after Alzheimer’s.

It is caused by abnormal protein deposits called Lewy bodies in the brain.

LBD affects memory, movement, behavior, and sleep patterns.

Early symptoms often mimic other neurological disorders.

While there is no cure, early diagnosis and care strategies can improve quality of life.

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Table of content

What is Lewy Body Dementia?

Common Symptoms of Lewy Body Dementia

Causes and Risk Factors

How is Lewy Body Dementia Diagnosed?

Treatment and Management Options

What is Lewy Body Dementia?

Lewy Body Dementia is a progressive neurodegenerative disease marked by the abnormal buildup of proteins known as Lewy bodies inside brain cells. These proteins interfere with brain functions, particularly those related to cognition, movement, and behavior.

LBD encompasses two related diagnoses:

Dementia with Lewy Bodies (DLB) — When cognitive symptoms appear before or at the same time as motor symptoms.

Parkinson’s Disease Dementia (PDD) — When motor symptoms precede cognitive decline by at least a year.

Both conditions share the same underlying pathology but differ in symptom progression and initial presentation.

Common Symptoms of Lewy Body Dementia

Lewy Body Dementia symptoms are diverse and often fluctuate from day to day, which can make diagnosis challenging. Here are the most commonly observed symptoms:

Cognitive Symptoms

Memory Loss: Although not as severe in early stages as in Alzheimer’s, short-term memory may be affected.

Attention Fluctuations: Patients may seem alert and coherent one moment and confused or unresponsive the next.

Executive Dysfunction: Difficulty with planning, problem-solving, and decision-making.

Visual-Spatial Problems: Trouble judging distances, recognizing objects, or navigating familiar environments.

Motor Symptoms

Parkinsonism: Slowed movement (bradykinesia), muscle stiffness, shuffling walk, and tremors similar to Parkinson’s disease.

Postural Instability: Increased risk of falls due to poor balance and coordination.

Visual Hallucinations

One of the hallmark features of LBD is vivid, well-formed visual hallucinations. Patients often see people, animals, or objects that aren’t there. These hallucinations are persistent and may become a daily occurrence.

Sleep Disturbances

REM Sleep Behavior Disorder (RBD): Acting out dreams during REM sleep, sometimes violently.

Daytime Drowsiness: Excessive sleepiness despite adequate nighttime sleep.

Mood and Behavioral Changes

Depression and Anxiety: Common in both early and advanced stages.

Apathy: Loss of motivation and interest in daily activities.

Paranoia and Delusions: False beliefs about people or situations, sometimes leading to agitation.

Causes and Risk Factors

The exact cause of Lewy Body Dementia remains unknown, but several factors appear to increase the risk:

Age: Most patients are over 60 years old.

Genetics: A family history of dementia or Parkinson’s may elevate risk, though most cases are sporadic.

Biological Factors: The presence of abnormal alpha-synuclein protein in the brain, which aggregates into Lewy bodies.

Environmental factors and overall brain health may also play roles, but research is ongoing.

How is Lewy Body Dementia Diagnosed?

Diagnosing LBD requires a careful evaluation since its symptoms overlap with other neurological conditions. The diagnostic process may include:

Detailed Medical History and Symptom Review

Neurological Examination

Cognitive and Memory Tests

Brain Imaging (MRI or CT scans) to rule out other conditions

Sleep Studies for REM sleep behavior disorder

Biomarker Tests (if available)

There is no single test to confirm LBD, making clinical expertise and careful observation essential.
 

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Treatment and Management Options

There is currently no cure for Lewy Body Dementia, but a combination of medication, therapy, and lifestyle adjustments can help manage symptoms:

Medications

Cholinesterase Inhibitors (e.g., donepezil, rivastigmine): Improve cognition and reduce hallucinations.

Levodopa: May help with motor symptoms but can worsen hallucinations.

Melatonin or Clonazepam: For REM sleep behavior disorder.

Antipsychotic Medications: Must be used with extreme caution due to severe side effects in LBD patients.

Non-Pharmacological Strategies

Physical Therapy: Helps maintain mobility and reduce fall risk.

Occupational Therapy: Supports daily living activities.

Cognitive Therapy: May help slow cognitive decline.

 

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